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TRANS-INTESTINAL ABSORPTION RATES DIFFER BETWEEN FREE AMINO ACIDS DURING LARVAL DEVELOPMENT IN ATLANTIC HERRING (CLUPEA HARENGUS)

Trans-intestinal absorption (TIA) rates for the free amino acids (FAA) alanine, proline, and glutamic acid were measured in two developmental phases of Atlantic herring larvae: Early(14–16 day-post-hatch) and Late (37–39 day-post-hatch). TIA rates were determined by measuring net uptake of a 14C-radiolabeled FAA tracer solution into the body after administration…

SENSORY PROPERTIES OF VEGETABLE DIETS AFFECT FEEDING PATTERN IN SEABREAM (SPARUS AURATA)

The steady growth of aquaculture production worldwide paired with reduced availability and escalating costs of feed ingredients from wild fisheries has foster the use of alternative ingredients in fish farming. Nevertheless, even if the nutritional profile covers basic requirements, there are often issues with acceptability of such feeds. This study…

SENSORY PROPERTIES OF VEGETABLE DIETS AFFECTS FEEDING PATTERNS IN SEABRAM (SPARUS AURATA)

The steady growth of aquaculture production worldwide paired with reduced availability and escalating costs of feed ingredients from wild fisheries has foster the use of alternative ingredients in fish farming. Nevertheless, even if the nutritional profile covers basic requirements, there are often issues with acceptability of such feeds. This study…

SECRETION OF GLUCAGON-LIKE PEPTIDE-2 RESPONDS TO NUTRIENT INTAKE BUT NOT GLUCOSE PROVISION IN MILK-FED CALVES

Glucagon-like peptide 2 (GLP-2) is a peptide released by the lower gut that has potent trophic and restorative effects on the intestinal epithelium. Two experiments were conducted to assess the effects of feeding rate and either metabolizable or nonmetabolizable glucose supplementation on GLP-2 concentrations in plasma and intestinal development in…

PIGLET GROWTH BEFORE WEANING HAS LONG-TERM EFFECTS ON INTESTINAL BARRIER FUNCTION

In mice, weaning stress increases intestinal permeability partly through a mechanism that involves TNF-α, intestinally-produced glucocorticoids, and myosin like chain kinase (MLCK). Recent evidence suggests that this interplay takes place predominantly in the colonic mucosa and has long-lasting effects on intestinal development and function. Interestingly, the impact of weaning-induced intestinal…

ENTERAL OBETICHOLIC ACID PREVENTS HEPATIC CHOLESTASIS IN TOTAL PARENTERAL NUTRITION-FED NEONATAL PIGS

Total parenteral nutrition (TPN) is a vital support for neonatal infants with congenital or acquired gastrointestinal (GI) disorders and requiring small bowel resection. An adverse outcome associated with prolonged TPN use is parenteral nutrition associated cholestasis (PNAC). We previously showed that enteral chenodeoxycholic acid (CDCA) treatment reduced PNAC. We hypothesized…