CHARACTERIZATION OF PORCINE UMAMI TASTE RECEPTORS (PT1R1 AND PT1R3)

CATEGORY: Feed Additives

DATE:June 2009

AUTHORS: Humprhey, B., Tedo, G., Roura, E. and Klasing, K.C.

BOOK/JOURNAL:Journées de la Recherche Porcine, 41: 15-16

ABSTRACT:

Umami is a taste quality sensing dietary protein born nutrients such as L-amino acids. Humans and mice perceive the umami taste via a trans-membrane heterodimeric receptor consisting of T1R1 and T1R3 proteins. Porcine umami taste receptors have been recently identified and reported in vallate papilla tissue samples. The pTas1r1 and pTas1r3 gene sequences were determined with a total number of 2535 and 2568 nucleotide, respectively and translated into their 844 and 855 amino acid composition of the protein receptors T1R1 and T1R3 respectively. Compared to the other mammals evaluated the porcine nucleotide and amino acid sequences were found to have the highest homology to the cat and cow umami receptors and the lowest to mouse and humans. According to our porcine T1R1 and T1R3 receptor characterization we conclude that human and/or mouse umami perception may not be a good model for pig umami sensing.

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